Himachal Newsline
Wednesday, March 22, 2023
No Result
View All Result
  • Home
  • Himachal Pradesh News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Social Work
    • Religion
Himachal Newsline
No Result
View All Result

Scientists devise a new tool to fight diarrhea

Himachal Newsline Desk by Himachal Newsline Desk
November 6, 2020
in Health & Fitness, Science
0 0
0
Share on FacebookShare on Twitter

New Delhi, (India Science Wire): E.coli is the most common foodborne bacteria causing illnesses including diarrhea, fever, and death if left undiagnosed and untreated, which makes its detection most important. Traditional detection methods such as culture or PCR are time-consuming and require skilled manpower. Antibody-based ELISA tests have also been developed but the instability of the antibodies, high cost, batch to batch variation, and complex synthesis method limits its application.

A team of researchers at DBT-National Agri-Food Biotechnology Institute (DBT-NABI), Mohali, has come up with a solution. They have developed a probe based on ssDNA aptamer. Aptamers are low molecular weight biomolecules widely used for bio-detection as they are stable, sensitive, selective, have low cost, and low batch to batch variation. They interact directly with the cell surface of the target rather than the nucleic acids and thus have the potential for whole bacteria detection.

RelatedPosts

Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services

Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services

March 20, 2023
Do rare Diseases account for the economic burden on India?

Do rare Diseases account for the economic burden on India?

March 20, 2023

The researchers conjugated the aptamer with gold nanoparticles (AuNPs) to enable detection with the naked eye. They also covered the gold nanoparticles with Graphene Oxide to improve upon the aptamer conjugation, thus augmenting the overall sensitivity of the probe.

The probe worked by a change in colour: it changed from red to blue within an hour of incubation with E.coli cells. The cells were detected up to a concentration of 1,000 cells per millilitre without Graphene Oxide coating. This substantially improved to a concentration of a mere 100 cells per millilitre with Graphene Oxide coating. The system was tried with coconut water samples and it worked well.

Speaking to India Science Wire, team leader, Dr.NitinSinghal, said the new probe could be used as a point of the care detection device. The method is simple, fast, and can be easily performed without any skilled manpower. “Some highly sensitive bacterial detection techniques like surface-enhanced Raman spectroscopy based biosensor, which detect 10 cells/ml are available. But, they involve sophisticated instruments and thus require professionals for handling”, he added.

The study was conducted in collaboration with the Institute of Microbial Technology (CSIR-IMTECH), Chandigarh, Panjab University, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, and Jain University, Jain Global Campus, Bengaluru. The team included Ms.Ritika Gupta, Dr.Amit Kumar, Dr.SandeepKuma, and Dr. Anil Kumar Pinakka. They have published a report on their work in Journal “Sensors and Actuators: B. Chemical”. (India Science Wire)

Previous Post

Train differently with the MMA Champion -Alan Fenandes

Next Post

Ministry of Earth Sciences conducts a webinar to mark the World Tsunami Awareness Day 2020

Himachal Newsline Desk

Himachal Newsline Desk

Related Posts

Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services
Health & Fitness

Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services

March 20, 2023
Do rare Diseases account for the economic burden on India?
Health & Fitness

Do rare Diseases account for the economic burden on India?

March 20, 2023
zPlus.care for all your healthcare needs
Health & Fitness

zPlus.care for all your healthcare needs

March 17, 2023
Narayana Health’s multi-location campaigns emphasize on Awareness and honour the spirit of Cancer Survivors
Health & Fitness

Narayana Health’s multi-location campaigns emphasize on Awareness and honour the spirit of Cancer Survivors

March 1, 2023
Dr. Gautam Allahbadia takes us through the IVF journey 
Health & Fitness

Dr. Gautam Allahbadia takes us through the IVF journey 

February 23, 2023
CanSupport Walk for Life – Stride Against Cancer
Health & Fitness

CanSupport Walk for Life – Stride Against Cancer

February 18, 2023
Next Post

Ministry of Earth Sciences conducts a webinar to mark the World Tsunami Awareness Day 2020

Growmax Wealth Management Services helps people maximize their financial returns by safeguarding their investments at utmost convenience

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recent Posts

  • Two unstoppable Indians are changing the world March 21, 2023
  • Meet Dr. Santhi Saravanan: An Accomplished Artist, Financial Advisor, and Inspirational Speaker March 21, 2023
  • Xpert Times Latest Project Aims to Inspire Youth through Celebrity Interviews March 21, 2023
  • Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services March 20, 2023
  • Do rare Diseases account for the economic burden on India? March 20, 2023

Categories

  • Agriculture (11)
  • App News (13)
  • Astrology (3)
  • Auto (15)
  • Business (440)
  • Education (100)
  • Entertainment (157)
  • Fashion & Beauty (33)
  • Finance/Money (25)
  • Food (17)
  • Himachal Pradesh News (1)
  • India (2)
  • Lifestyle (427)
    • Health & Fitness (168)
    • Photography (5)
    • Travel (24)
  • National (119)
  • Politics (3)
  • Press Release (5)
  • Religion (4)
  • Science (94)
  • Social Work (32)
  • Sports (38)
  • State News (69)
  • Tech (61)
  • World (10)

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Health & Fitness
  • Himachal Pradesh News
  • India
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World

Recent News

  • Two unstoppable Indians are changing the world
  • Meet Dr. Santhi Saravanan: An Accomplished Artist, Financial Advisor, and Inspirational Speaker
  • Xpert Times Latest Project Aims to Inspire Youth through Celebrity Interviews
  • Japan-based Toyota Tsusho Corporation and Tokai Corp Partner to Launch Valabhi Hospital Services
  • Do rare Diseases account for the economic burden on India?
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Himachal Newsline

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Himachal Newsline

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In