Himachal Newsline
Saturday, June 14, 2025
No Result
View All Result
  • Home
  • Himachal Pradesh News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Social Work
    • Religion
Himachal Newsline
No Result
View All Result

IIT-Indore scientists uncover a new approach to inhibit Zika virus replication

Himachal Newsline Desk by Himachal Newsline Desk
January 13, 2021
in Health & Fitness
0 0
0
Share on FacebookShare on Twitter

New Delhi (India Science Wire): Efforts to find an effective treatment for the Zika virus could get a boost with researchers at the Indian Institute of Technology-Indore (IIT-Indore) identifying some structures in the genetic makeup of the virus that could be used as targets for drugs. 

The COVID-19 pandemic has highlighted the threat posed by emerging and re-emerging diseases to public health across the world. This has led to an increase in the focus of medical research on the development of effective drugs and vaccines against them. Zika is one such virus. The World Health Organisation (WHO) had declared it as a public health emergency of international concern after an outbreak in Brazil in 2015.

RelatedPosts

Visionary Leadership: Padmaja T’s Unstoppable Mission to Revolutionize Global Pet Care

Visionary Leadership: Padmaja T’s Unstoppable Mission to Revolutionize Global Pet Care

May 24, 2025
Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

May 22, 2025

Zika is a mosquito-borne virus. Around 86 countries have reported cases of Zika to date, thus making it a major cause for concern.  It is found to be associated with neurological complications like Microcephaly in children and Guillain-Barré syndrome in adults. Studies have also shown that infection in pregnant women may lead to congenital abnormalities in the developing fetus or the neonates. However, at present, there is no specific vaccine or medicine for Zika virus. 

A recent study by a team of scientists from IIT Indore promises to help address the problem. They have identified specific secondary structures called G-quadruplexes (GQ) in the RNA of the virus that could act as drug binding sites. These structures made of nucleic acids have proven to be effective drug-targeting sites for anti-cancer treatment and is recently being explored for other diseases as well. 

In association with a research group from the University of Nebraska-Lincoln, USA, the team has also characterized and evaluated the interaction patterns of the genetic sequences in the virus that form the G-quadruplex structures with some drug molecules. 

Speaking to India Science Wire, Dr. Amit Kumar and Dr. Debasis Nayak, from IIT Indore who conceptualized the work along with Prof. Asit K. Pattnaik from University of Nebraska-Lincoln, USA, said, “We treated cells infected with the virus and found a significant decrease in the viral replication and in turn in the viral growth. It is clear that the molecules are effective against the virus. Our study can open up new avenues for control and mitigation of Zika virus”. 

Asked about their future plans, they said that they were searching for more small molecules targeting the Zika virus secondary structures that can act as potential antiviral drug candidates against Zika virus without affecting the host cells.

A report on the research work was recently published in Molecular Therapy-Nucleic Acids (Cell Press). The team included Prativa Majee, Uma Shankar from IIT Indore and Aryamav Pattnaik, and Bikash R. Sahoo from University of Nebraska-Lincoln, USA, besides Dr. Amit Kumar, and Dr. Debasis Nayak and Prof. Asit K. Pattnaik. (India Science Wire)

Tags: cancercellcongenital abnormalitiesdiseasedrugfetusgeneticGuillain-Barré syndromeMicrocephalymosquito-borneneonatesneurological complicationsRNAvaccineWHO
Previous Post

Holding breath may increase risk of getting COVID-19 Infection

Next Post

3th India-Vietnam Defence Security Dialogue

Himachal Newsline Desk

Himachal Newsline Desk

Related Posts

Visionary Leadership: Padmaja T’s Unstoppable Mission to Revolutionize Global Pet Care
Health & Fitness

Visionary Leadership: Padmaja T’s Unstoppable Mission to Revolutionize Global Pet Care

May 24, 2025
Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment
Health & Fitness

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

May 22, 2025
STAR Hospitals, Nanakramguda Launches New-Gen Robotic Surgery System for Joint Replacement Surgery
Health & Fitness

STAR Hospitals, Nanakramguda Launches New-Gen Robotic Surgery System for Joint Replacement Surgery

May 21, 2025
First-of-its-Kind Case in India: Malla Reddy Narayana Cancer Hospital Successfully Treats Primary Peritoneal Ewing’s Sarcoma with Advanced HIPEC Surgery
Health & Fitness

First-of-its-Kind Case in India: Malla Reddy Narayana Cancer Hospital Successfully Treats Primary Peritoneal Ewing’s Sarcoma with Advanced HIPEC Surgery

April 21, 2025
Svdaa: The New Benchmark in Luxury Skincare
Health & Fitness

Svdaa: The New Benchmark in Luxury Skincare

March 12, 2025
Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP
Health & Fitness

Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

December 12, 2023
Next Post

3th India-Vietnam Defence Security Dialogue

Dr. Harsh Vardhan inaugurates the first the Grand Finale of the Red Ribbon Quiz Competition organized by NACO and MoHFW

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recent Posts

  • Viamigos.com: The Ultimate Platform for the Cheapest Round-Trip International Flight Deals from Major Indian Cities June 12, 2025
  • Sundried, Supercharged & Seriously Tasty, That’s Hale & Hearty Ragi Noodles ! June 10, 2025
  • Peak Bengaluru Moment: Bengaluru Rapido Driver’s Anti-Rohan Message Breaks the Internet June 7, 2025
  • Public Bytes TV Sees Unmatched Growth Across Regional News Markets June 7, 2025
  • 5 Benefits of Applying for a Personal Loan Online June 7, 2025

Categories

  • Agriculture (13)
  • App News (13)
  • Astrology (5)
  • Auto (17)
  • Business (568)
  • Education (128)
  • Entertainment (181)
  • Fashion & Beauty (38)
  • Finance/Money (32)
  • Food (22)
  • Himachal Pradesh News (4)
  • India (2)
  • Lifestyle (506)
    • Health & Fitness (187)
    • Photography (6)
    • Travel (33)
  • National (122)
  • Politics (5)
  • Press Release (24)
  • Religion (11)
  • Science (94)
  • Social Work (44)
  • Sports (49)
  • State News (73)
  • Tech (75)
  • World (18)

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Health & Fitness
  • Himachal Pradesh News
  • India
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World

Recent News

  • Viamigos.com: The Ultimate Platform for the Cheapest Round-Trip International Flight Deals from Major Indian Cities
  • Sundried, Supercharged & Seriously Tasty, That’s Hale & Hearty Ragi Noodles !
  • Peak Bengaluru Moment: Bengaluru Rapido Driver’s Anti-Rohan Message Breaks the Internet
  • Public Bytes TV Sees Unmatched Growth Across Regional News Markets
  • 5 Benefits of Applying for a Personal Loan Online
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Himachal Newsline

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Himachal Newsline

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In